Our research focuses on the mechanisms driving the observed epidemiological patterns of pneumococcal disease. Pneumococcus causes a large burden of disease worldwide, particularly among young children and the elderly. Major research questions in the lab are related to long-term bacterial evolution, impacts of immunization on carriage and disease in different populations, and seasonal determinants of bacterial disease incidence (including viral co-infections and carriage). These projects utilize both quantitative tools and experimental laboratory studies. You can learn more about our research and recent publications here.